Browsing by Organisational Unit "FB 08 - Biologie und Chemie"
Now showing items 41-60 of 69
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Novel scalable approaches for the computational analysis of bacterial genomes
(2021)Over the last decades, the giant progress of DNA sequencing led to increased throughput and tremendously reduced costs resulting in a broad accessibility and applicability of these technologies and thus revolutionized the ... -
Oxazaborolidines in Organocatalysis - The Importance of Noncovalent Interactions in the Corey-Bakshi-Shibata Reduction
(2022)Part 1: Oxazaborolidines in Organocatalysis The major part of this thesis deals with oxazaborolidines (OXB) as chiral organocatalysts for asymmetric Diels-Alder reactions and Corey-Bakshi-Shibata reductions. In order to ... -
Oxidative posttranslationale Redoxmodifikationen in Plasmodium falciparum
(2021-03)Das die Infektionskrankheit Malaria auslösende Protozoon Plasmodium ist seit langem Mittelpunkt intensiver Forschung. Bisher sind seine Biologie, Biochemie und die Interaktion mit dem Wirt nicht vollständig verstanden. Die ... -
Pathogenerkennung durch solitäre chemosensorische Zellen und Koppelung an die mukoziliäre Clearance
(2022)Die Mukoziliäre Clearance (MC) stellt den primären Abwehrmechanismus in den Atemwegen dar, welcher für den Abtransport von eingeatmeten Mikroorgansimen, Allergenen und Partikeln verantwortlich ist. Die MC wird durch den ... -
Posttranskriptionelle Genregulation in α-Proteobakterien : neue Aspekte zu der kleinen RNA StsR und dem DUF1127 Protein CcaF1 in Rhodobacter sphaeroides
(2021-11)Mikroorganismen passen ihre Genexpression den schnell wechselnden Bedingungen in ihrem Lebensraum an. Dazu besitzen Bakterien komplexe transkriptionelle und posttranskriptionelle Regulationsmechanismen, die ihnen eine ... -
Promoting heart regeneration via cardiomyocyte-specific OSKM-expression
(2022)Cardiomyocytes are critically responsible for heart contraction and the pumping of blood through the circulatory system. In adult mice and humans, the rate of cardiomyocyte division is extremely low. In addition, dedicated ... -
Reaction Mechanisms at Cathodes in Lithium/Oxygen Batteries
(2021-12)Aprotic lithium/oxygen (Li/O2) batteries are still seen as a highly promising technology for mobile energy storage, as they, in theory, exceed the theoretical energy density of state-of-the-art lithium-ion batteries (LIBs) ... -
Regulation des Katabolismus von verzweigtkettigen Aminosäuren durch die lange nicht-kodierende RNA mito-lnc
(2020-09)Die funktionelle Analyse von langen, nicht-kodierenden RNAs (lncRNAs) und ihrer Rolle bei der Regulation der metabolischen Homöostase liefern bedeutsame Einblicke in diverse metabolische Regelkreise. Die vorliegende Arbeit ... -
Ruthenium-iridium mixed oxides RuxIr1-xO2 prepared by sol-gel method and applied to catalytic methane combustion
(2021)The mechanism of the methane combustion reaction is split into an initial activation of the C H bond to form methyl (CH3) and methylene (CH2), followed by either a direct oxidation to CO2 or alternatively to the formation ... -
Sirt7 acts as a novel regulator of chromatin dynamics through modulation of the Sirt1/Suv39H1 axis: Possible role in cancer
(2020)Sirtuins build a family of NAD+-dependent histone and protein deacetylases that are involved in a variety of cellular processes including proliferation, metabolism, genomic stability and stress response among others. ... -
Spurious transcripts in Tet3-deficient smooth muscle cells provoke innate immune responses and lung pathogenesis
(2021)Initiation of transcription at the regular start site is critical for the generation of functional transcripts, preventing production of aberrant and potentially hazardous aberrant RNAs. Here, we demonstrate that TET3, ... -
Structure Data for "Increased molecular inhomogeneity and cluster glass formation as a basis for inexpensive white-light production"
(2022-03-04)Calculated structural data of monomers and dimers of cluster materials for the publication: Irán Rojas-León, Jan Christmann, Sebastian Schwan, Ferdinand Ziese, Simone Sanna, Doreen Mollenhauer, Nils W. Rosemann, Stefanie ... -
Studie Beobachtung und Vergleich des Verhaltens von Betta splendens Männchen in 35 L und 55 L Aquarien
(2022-03)In einer Studie des Buntbarschlabors (Schülerlabors) des Instituts für Biologiedidaktik wurden von Studierenden mehrere Exemplare männlicher Kampffische der Art Betta splendens über mehrere Monate unter vergleichbaren ... -
Surface Coatings of Nickel-Rich NCM Based Cathode Active Materials for Improved Electrochemical Performance of Lithium-Ion Batteries
(2021-09)Ni-rich NCM based cathodes are considered the most promising cathode candidates for next-generation high-performance Lithium-ion batteries (LIBs). Despite very good electrochemical performance, Ni-rich NCM based cathodes ... -
Sustainability in Organic Synthesis - Bidentate Lewis Acid Inverse Electron-Demand Diels-Alder Reactions and the Synthesis of Organic Redox Flow Battery Electrolyte Materials
(2021)Sustainable development in organic chemistry is driven by limited fossil raw materials, waste production and environmental pollution. The waste issue can be solved by catalysed one-step reactions, which are more sustainable ... -
Die synergistische Wirkung von miR-1/133a ist für die Aufrechterhaltung des postmitotischen Zustandes adulter Kardiomyozyten essenziell
(2021)Die Funktion des Herz-Kreislauf-Systems ist von grundlegender Bedeutung für die Versorgung des Organismus mit Sauerstoff und Nährstoffen. Die Pumpleistung des Herzens wird durch hochspezialisierte kontraktile Kardiomyozyten ... -
Synthesis of (Nor)-Adamantane Derivatives via [1,2]-Alkyl Migration Reactions
(2021)In this thesis, selected results on the rearrangement between the noradamantane and the adamantane hydrocarbon cage are presented, as well as their application in organic synthesis. This reversible reaction proceeds through ... -
Synthetic and mechanistic investigations of copper and iron complexes with ‘small’ tripodal, aliphatic N-donor ligands and their reactivity towards dioxygen
(2021)Die vorliegende Arbeit befasst sich mit der Modellierung von Ligandensystemen, welche sodann mit Kupfer- bzw. Eisensalzen unter Sauerstoffausschluss zu niedrig oxidierten Precursor-Komplexen umgesetzt wurden, um bei einer ... -
Systematic investigation of Pimpinella saxifraga in Germany
(2022)Introduction: This study focuses on Pimpinella saxifraga L. (Apiaceae), native in Germany. Pimpinella contains about 180 species all over the world being one of the largest genera in the Apiaceae. Due to large morphological ... -
The interplay of RNases and sRNAs contributes to a complex layer of post-transcriptional gene regulation in proteobacteria
(2021-12)Bacteria face constantly changing environmental conditions, like changes in temperature or exposure to oxidative stress. Since bacterial cells have only limited options to physically escape, a rapid adaption to the ...