Browsing by Author "Konrad, Lutz"
Now showing items 1-16 of 16
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Activin A Modulates Betaglycan Shedding via the ALK4-SMAD3-Dependent Pathway in Endometriotic Cells
Mwaura, Agnes N.; Riaz, Muhammad A.; Maoga, Jane B.; Mecha, Ezekiel; Omwandho, Charles O. A.; Scheiner-Bobis, Georgios; Meinhold-Heerlein, Ivo; Konrad, Lutz (2022) -
Betaglycan (TßRIII) is a Key Factor in TGF-ß2 Signaling in Prepubertal Rat Sertoli Cells
Kudipudi, Pradeep; Galuska, Sebastian Peter; Dietze, Raimund; Scheiner-Bobis, Georgios; Loveland, Katherine L.; Konrad, Lutz (2019) -
Claudin-10 Expression Is Increased in Endometriosis and Adenomyosis and Mislocalized in Ectopic Endometriosis
Loeffelmann, Anna C.; Hoerscher, Alena; Riaz, Muhammad A.; Zeppernick, Felix; Meinhold-Heerlein, Ivo; Konrad, Lutz (2022) -
Epithelial-Mesenchymal Transition in Endometriosis - When Does It Happen?
Konrad, Lutz; Dietze, Raimund; Riaz, Muhammad A.; Scheiner-Bobis, Georgios; Behnke, Judith; Horné, Fabian; Hoerscher, Alena; Reising, Christoph; Meinhold-Heerlein, Ivo (2020) -
Expressionsprofile von Vimentin, Claudin-11 und Claudin-7 in der Pathogenese der Endometriose
Horné, Fabian (2020)Obwohl Endometriose für bis zu 10 % aller Frauen im reproduktiven Alter eine erhebliche Einschränkung der Lebensqualität und Bedrohung ihrer Fertilität darstellt, ist die Pathogenese dieser chronischen Erkrankung nach wie ... -
Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis
Stammler, Angelika; Lüftner, Benjamin Udo; Kliesch, Sabine; Weidner, Wolfgang; Bergmann, Martin; Middendorff, Ralf; Konrad, Lutz (2016)In this study we tested expression of tight junction proteins in human, mouse and rat and analyzed the localization of claudin-11 in testis of patients with normal and impaired spermatogenesis. Recent concepts generated ... -
Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis
Maoga, Jane B.; Riaz, Muhammad A.; Mwaura, Agnes N.; Scheiner-Bobis, Georgios; Mecha, Ezekiel; Omwandho, Charles O. A.; Meinhold-Heerlein, Ivo; Konrad, Lutz (2022) -
Long-Term Maintenance of Viable Adult Rat Sertoli Cells Able to Establish Testis Barrier Components and Function in Response to Androgens
Kabbesh, Hassan; Riaz, Muhammad A.; Jensen, Alexandra; Scheiner-Bobis, Georgios; Konrad, Lutz (2021) -
Membrane-type matrix metalloproteinases: membrane-type 1 matrix metalloproteinase, membrane-type 2 matrix metalloproteinase and membrane-type 3 matrix metalloproteinase in endometriosis and adenomyosis
Maoga, Jane Bosibori (2023)Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue; endometrial glands and stroma outside the uterus. Even though endometriosis affects about 0.7-8.6% women of the reproductive ... -
PAI-1 secretion of endometrial and endometriotic cells is Smad2/3- and ERK1/2-dependent and influences cell adhesion
Sui, Cong; Mecha, Ezekiel; Omwandho, Charles O. A.; Starzinski-Powitz, Anna; Stammler, Angelika; Tinneberg, Hans-Rudolf; Konrad, Lutz (2016)In the endometrium transforming growth factor-betas (TGF-ßs) are involved mainly in menstruation and endometriosis. After binding of the ligands to the high-affinity receptors, TGF-ß receptors (TBR1 and TBR2), TGF-ßs ... -
Predictive Model for the Non-Invasive Diagnosis of Endometriosis Based on Clinical Parameters
Konrad, Lutz; Fruhmann Berger, Lea M.; Maier, Veronica; Horné, Fabian; Neuheisel, Laura M.; Laucks, Elisa V.; Riaz, Muhammad A.; Oehmke, Frank; Meinhold-Heerlein, Ivo; Zeppernick, Felix (2023)Objectives: Are other pain symptoms in addition to dysmenorrhea, dyspareunia, dyschezia, dysuria, and chronic pelvic pain correlated to endometriosis and suitable for a clinical prediction model? Methods: We conducted a ... -
Role of Betaglycan in TGF-ß Signaling and Wound Healing in Human Endometriotic Epithelial Cells and in Endometriosis
Mwaura, Agnes N.; Riaz, Muhammad A.; Maoga, Jane B.; Mecha, Ezekiel; Omwandho, Charles O. A.; Scheiner-Bobis, Georgios; Meinhold-Heerlein, Ivo; Konrad, Lutz (2022) -
The Importance of Stromal Endometriosis in Thoracic Endometriosis
Mecha, Ezekiel; Makunja, Roselydiah; Maoga, Jane B.; Mwaura, Agnes N.; Riaz, Muhammad A.; Omwandho, Charles O. A.; Meinhold-Heerlein, Ivo; Konrad, Lutz (2021) -
The Type III Transforming Growth Factor-β receptor (Betaglycan or BG) Modulates TGF-β Signaling and Wound Healing in Human Endometrial Cells and in Endometriosis
Mwaura, Agnes Njoki (2023)Endometriosis is an estrogen-responsive disease defined as the presence of endometrial tissue at ectopic sites. TGF-β superfamily members are pleiotropic cytokines that exhibit cell-type-specific effects and regulate a ... -
Time-lapse imaging as a tool to investigate contractility of the epididymal duct : effects of Cgmp signaling
Mietens, Andrea; Tasch, Sabine; Stammler, Angelika; Konrad, Lutz; Feuerstacke, Caroline; Middendorff, Ralf (2014)The well orchestrated function of epididymal smooth muscle cells ensures transit of spermatozoa through the epididymal duct during which spermatozoa acquire motility and fertilizing capacity. Relaxation of smooth muscle ... -
Vergleich von Schmerzmarkern im endometriotischen Gewebe und Charakterisierung des subjektiven Schmerzempfindens der Patientinnen
Fruhmann Berger, Lea Manina (2022)Die Endometriose (EM) ist eine gynäkologische Erkrankung, die durch endometriotisches Gewebe außerhalb des Cavum Uteri gekennzeichnet ist. Als Leitsymptome gelten die Dysmenorrhoe, der chronische Unterbauchschmerz und die ...