Auflistung nach Autor "Rath, Timo"
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Assessment of pathologic increase in liver stiffness enables earlier diagnosis of CFLD: Results from a prospective longitudinal cohort study
Klotter, Victoria; Gunchick, Caroline; Siemers, Enno; Rath, Timo; Hudel, Helge; Naehrlich, Lutz; Roderfeld, Martin; Roeb, Elke (2017)About 30% of patients with Cystic Fibrosis (CF) develop CF-associated liver disease (CFLD). Recent studies have shown that transient elastography (TE), as a method to quantify liver stiffness, allows non-invasive diagnosis ... -
Identification of neutrophil activation markers as novel surrogate markers of CF lung disease
Rath, Timo; Zwaschka, Lisa; Hage, Lisa; Kügler, Marion; Menendez, Katrin; Naehrlich, Lutz; Schulz, Richard; Roderfeld, Martin; Roeb, Elke (2014)Background and aims: Cystic Fibrosis (CF) lung disease is characterized by progressively declining lung function and represents a major factor contributing to the high morbidity and mortality associated with CF. However, ... -
IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice
Hahn, Luisa; Helmrich, Nora; Herebian, Diran; Mayatepek, Ertan; Drebber, Uta; Domann, Eugen; Olejniczak, Stefan; Weigel, Markus; Hain, Torsten; Rath, Timo; Wirtz, Stefan; Mollenkopf, Hans-Joachim; Schmidt, Nadine; Ewers, Christa; Baier, Anne; Churin, Yuri; Windhorst, Anita Cornelia; Weiskirchen, Ralf; Steinhoff, Ulrich; Roeb, Elke; Roderfeld, Martin (2020) -
Presence of intestinal Mycobacterium avium subspecies paratuberculosis (MAP) DNA is not associated with altered MMP expression in ulcerative colitis
Rath, Timo; Roderfeld, Martin; Blöcher, Sonja; Rhode, Annika; Basler, Tina; Akineden, Ömer; Abdulmawjood, Amir; Halwe, Jörg M; Goethe, Ralph; Bülte, Michael; Roeb, Elke (2011)Background: Mycobacterium avium subspecies paratuberculosis (MAP) is suspected to be a causative agent in human Crohn´s disease (CD). Recent evidence suggests that pathogenic mycobacteria and MAP can induce the expression ... -
Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease
Rath, Timo; Hage, Lisa; Kügler, Marion; Menendez Menendez, Katrin; Zachoval, Reinhart; Naehrlich, Lutz; Schulz, Richard; Roderfeld, Martin; Roeb, Elke (2013)Background and Aims Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify ... -
Systemic and mucosal immune reactivity upon Mycobacterium avium ssp. paratuberculosis infection in mice
Koc, Arzu; Bargen, Imke; Suwandi, Abdulhadi; Roderfeld, Martin; Tschuschner, Annette; Rath, Timo; Gerlach, Gerald F.; Hornef, Mathias; Goethe, Ralph; Weiss, Siegfried; Roeb, Elke (2014)Mycobacterium avium ssp. paratuberculosis (MAP) is the cause of Johne´s disease, an inflammatory bowel disorder of ruminants. Due to the similar pathology, MAP was also suggested to cause Crohn´s disease (CD). Despite of ...