Browsing by Author "Tag, Claudia"
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Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin.
Dietel, Eric; Brobeil, Alexander; Delventhal, Lucas; Tag, Claudia; Gattenlöhner, Stefan; Wimmer, Monika (2019)LDC3/Dynarrestin, an aminothiazole derivative, is a recently developed small molecule, which binds protein tyrosine phosphatase interacting protein 51 (PTPIP51). PTPIP51 interacts with various proteins regulating different ... -
Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells
Dietel, Eric; Brobeil, Alexander; Tag, Claudia; Gattenloehner, Stefan; Wimmer, Monika (2018)Breast cancer is the most common female cancerous disease and the second most cause of cancer death in women. About 20-30% of these tumors exhibit an amplification of the HER2/ErbB2 receptor, which is coupled to a more ... -
PTPIP51 crosslinks the NFκB signaling and the MAPK pathway in SKBR3 cells
Dietel, Eric; Brobeil, Alexander; Tag, Claudia; Gattenlöhner, Stefan; Wimmer, Monika (2020)