Browsing by Author "Yakoob, Sanaria Hawro"

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Activation of endothelial NO synthase and P2X7 receptor modification mediates the cholinergic control of ATP-induced interleukin-1ß release by mononuclear phagocytes

Richter, Katrin; Asci, Nilay; Singh, Vijay K.; Yakoob, Sanaria Hawro; Meixner, Marion; Zakrzewicz, Anna; Liese, Juliane; Hecker, Andreas; Wilker, Sigrid; Stumpf, Sabine; Schlüter, Klaus-Dieter; Rohde, Marius; Gödecke, Axel; Padberg, Winfried; Manzini, Ivan; Schmalzing, Günther; Grau, Veronika (2023)

Objective: The pro-inflammatory cytokine interleukin-1β (IL-1β) plays a central role in host defense against infections. High systemic IL-1β levels, however, promote the pathogenesis of inflammatory disorders. Therefore, ...