Auflistung JLUdocs nach Autor "Damm, Jelena"
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Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain
Fuchs, Franziska; Damm, Jelena; Gerstberger, Rudiger; Roth, Joachim; Rummel, Christoph (2013)BACKGROUND:The transcription factor nuclear factor interleukin 6 (NF-IL6) is known to be activated by various inflammatory stimuli in the brain. Interestingly, we recently detected NF-IL6-activation within the hypothalam ... -
beta-Nicotinamide Adenine Dinucleotide (beta-NAD) Inhibits ATP-Dependent IL-1beta Release from Human Monocytic Cells
Hiller, Sebastian Daniel; Heldmann, Sarah; Richter, Katrin; Jurastow, Innokentij; Küllmar, Mira; Hecker, Andreas; Wilker, Sigrid; Fuchs-Moll, Gabriele; Manzini, Ivan; Schmalzing, Günther; Kummer, Wolfgang; Padberg, Winfried; McIntosh, J. Michael; Damm, Jelena; Zakrzewicz, Anna; Grau, Veronika (2018)While interleukin-1beta (IL-1beta) is a potent pro-inflammatory cytokine essential for host defense, high systemic levels cause life-threatening inflammatory syndromes. ATP, a stimulus of IL-1beta maturation, is released ... -
C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation
Richter, Katrin; Sagawe, Sabrina; Hecker, Andreas; Küllmar, Mira; Askevold, Ingolf; Damm, Jelena; Heldmann, Sarah; Pöhlmann, Michael; Ruhrmann, Sophie; Sander, Michael; Schlüter, Klaus-Dieter; Wilker, Sigrid; König, Inke R.; Kummer, Wolfgang; Padberg, Winfried; Hone, Arik J.; McIntosh, J. Michael; Zakrzewicz, Anna Teresa; Koch, Christian; Grau, Veronika (2018)Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but the biological functions of CRP are still controversial. CRP is a phosphocholine (PC)-binding ... -
Charakterisierung der Beteiligung des Transkriptionsfaktors NF-IL6 an der Induktion zentralnervös kontrollierter Krankheitssymptome in der Ratte
Damm, Jelena (2012)Systemische Entzündungsreaktionen gehen mit charakteristischen Symptomen wie Fieber, Anorexie, Adipsie, Lethargie und Verminderung der Körpermasse einher. Diese unterliegen der zentralnervösen Kontrolle und werden ... -
LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein
Peek, Verena; Harden, Lois M.; Damm, Jelena; Aslani, Ferial; Leisengang, Stephan; Roth, Joachim; Gerstberger, Rüdiger; Meurer, Marita; Köckritz-Blickwede, Maren von; Schulz, Sabine; Spengler, Bernhard; Rummel, Christoph (2021) -
SLPI Inhibits ATP-Mediated Maturation of IL-1beta in Human Monocytic Leukocytes: A Novel Function of an Old Player
Zakrzewicz, Anna; Richter, Katrin; Zakrzewicz, Dariusz; Siebers, Kathrin; Damm, Jelena; Agne, Alisa; Hecker, Andreas; McIntosh, J. Michael; Chamulitrat, Walee; Krasteva-Christ, Gabriela; Manzini, Ivan; Tikkanen, Ritva; Padberg, Winfried; Janciauskiene, Sabina; Grau, Veronika (2019)Interleukin-1beta (IL-1beta) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection. However, elevated circulating levels of IL-1beta can cause ...