Browsing JLUdocs by Author "Hake, Sandra B."
Now showing items 1-5 of 5
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Deciphering the Notch Pathway: A Bioinformatics Analysis of the RBPJ/Notch Axis
Friedrich, Tobias (2023)Notch-mediated signal transduction plays a pivotal role for multiple biological processes in development, differentiation and cell homeostasis. Its dysregulation has been linked to several diseases, including different ... -
JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions
Procida, Tara; Friedrich, Tobias; Jack, Antonia P. M.; Peritore, Martina; Bönisch, Clemens; Eberl, Hans Christian; Daus, Nadine; Kletenkov, Konstantin; Nist, Andrea; Stiewe, Thorsten; Borggrefe, Tilman; Mann, Matthias; Bartkuhn, Marek; Hake, Sandra B. (2021) -
JAZF1: a novel p400/TIP60/NuA4 complex member involved in the acetylation of H2A.Z
Procida, Tara (2021)In the nucleus of eukaryotic cells, the DNA occurs with histone proteins that package the DNA into the repeating subunit of chromatin, the nucleosome. This basic functional entity consists of two copies of each canonical ... -
The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs
Herchenröther, Andreas; Gossen, Stefanie; Friedrich, Tobias; Reim, Alexander; Daus, Nadine; Diegmüller, Felix; Leers, Jörg; Sani, Hakimeh Moghaddas; Gerstner, Sarah; Schwarz, Leah; Stellmacher, Inga; Szymkowiak, Laura Victoria; Nist, Andrea; Stiewe, Thorsten; Borggrefe, Tilman; Mann, Matthias; Mackay, Joel P.; Bartkuhn, Marek; Borchers, Annette; Lan, Jie; Hake, Sandra B. (2023)Specialized chromatin-binding proteins are required for DNA-based processes during development. We recently established PWWP2A as a direct histone variant H2A.Z interactor involved in mitosis and craniofacial development. ... -
The H2A.Z and PWWP2A associated NuRD interactor HMG20A controls transcriptional programs in head and heart development
Herchenröther, Andreas (2023)The inheritable information of all eukaryotic organisms is organized in DNA-protein complexes called chromatin. Dedicated chromatin-binding proteins are required for DNA-based processes during development. The recently ...