Herold, SusanneSchäfer, Theresa M.Theresa M.Schäfer2025-07-222025-07-222025https://jlupub.ub.uni-giessen.de/handle/jlupub/20725https://doi.org/10.22029/jlupub-20075Granulocyte-macrophage colony-stimulating factor (GM-CSF) exerts protective effects on bronchioalveolar stem cells (BASC) and alveolar epithelial cells type II (AECII) following viral lung injury by downregulating AMP-activated protein kinase (AMPK) signaling, which activates mechanistic target of rapamycin complex 1 (mTORC1). This activation supports the proliferation of epithelial stem cells and aids in the restoration of alveolar barrier function.enIn Copyrightlung researchinfectiologyacute lung injuryddc:500ddc:570ddc:610The impact of granulocyte-macrophage colony-stimulating factor on lung epithelial cell injury and repair in severe influenza virus pneumonia