Griwatz, Jan H.Jan H.GriwatzCampi, Chiara E.Chiara E.CampiKunz, AnneAnneKunzWegner, Hermann A.Hermann A.Wegner2024-11-262024-11-262024https://jlupub.ub.uni-giessen.de/handle/jlupub/19917https://doi.org/10.22029/jlupub-19272Molecular switches, especially azobenzenes, are used in numerous applications, such as molecular solar thermal storage (MOST) systems and photopharmacology. The Baeyer-Mills reaction of anilines and nitrosobenzenes has been established as an efficient synthetic method for non-symmetric azobenzenes. However, nitrosobenzenes are not stable, depending on their substitution pattern and pose a health risk. An in-situ oxidation of anilines with Oxone® was optimized under continuous flow conditions avoiding isolation and contact. The in-situ generated nitrosobenzene derivatives were subjected to a telescoped Baeyer-Mills reaction in flow. That way azobenzenes with a broad substituent spectrum were made accessible.enNamensnennung - Nicht kommerziell 4.0 Internationalddc:540