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Future theft : fossil capitalization, ecological dispossession, and climate reparations
(2025) Folkers, Andreas
Diagnostic challenge in veterinary pathology : generalized alopecia in a Holstein dairy cow
(2025) Hildebrand, Mirjam; Schäfer, Laura; Kübler, Isabelle; Henrich, Manfred; Welle, Monika; Linder, Keith E.; Venjakob, Peter L.
Disease outcomes following lateral switch among different CD20-antibodies in active multiple sclerosis
(2025) Axhausen, Franziska; Mrochen, Anne; Winter, Pia; Baumgart, Romy; Mühlenbrock, Pauline; Mück, Anne; Wolff, Stephanie; Meuth, Sven G.; Möllenhoff, Kathrin; Pfeuffer, Steffen
Background: Ocrelizumab (OCR) and ofatumumab (OFA) are approved and their differences in dosing route and interval allow personalized treatment. However, there are no data on whether lateral switches between both substances affect treatment effectiveness or safety. Methods: We screened our local cohort of MS patients, who began OCR since 09/2020 or OFA since 09/2021. Patients with a lateral switch were matched to controls who continuously received initial B-cell depleting therapy (BCT). We compared disease courses including effectiveness outcomes as well as peripheral CD19+ B-cell counts and serum IgG levels. Results: From 09/2020 to 03/2024, 713 patients were subjected to BCT (OCR: 396; OFA: 317 [as in Fig.1]). The matched OCR cohort included 38 switchers and 149 controls. The OFA cohort consisted of 24 switchers and 83 controls. Effectiveness outcomes were comparable among switchers and controls. B cell depletion appeared slightly pronounced following a switch. Serum IgG levels declined faster among switchers compared to controls (OCR: 9.7 vs 9.0 g/L; p = 0.007; manifest hypogammaglobulinemia (HGG) in 13.2% vs 6.0%; OFA: 9.7 vs 8.4 g/L; p = 0.016; manifest HGG in 8.3% vs 2.4%). Conclusions: Lateral switching between BCT does not abate effectiveness in this matched real-world cohort. Our observation of increased loss of IgG warrants further validation, but may indicate niche-specific immunological effects of OFA and OCR.
When topics of protest and counter-protest diverge : asymmetrical issue contestation in left-right street confrontations
(2025) Daria Meier, Larissa; Haunss, Sebastian; Daphi, Priska; Dollbaum, Jan Matti
Works on protest counter-protest dynamics tend to assume that protesters and counter-protesters make competing claims about the same issue. This paper challenges this basic assumption. Based on an original dataset on local protests in Germany, it demonstrates that events that trigger a counter-protest and the response event, that is, the counter-protest, differ significantly in the issues they address. While a range of issues elicit counter-protests, the response events generally mobilize around anti-far-right claims, even if the initial protest does not explicitly advance fascism/racism issues. We argue that the observed asymmetry results from the way counter-protests have historically emerged as a specific repertoire used by left-wing actors to oppose fascist/racist groups and claims.
Composite protests of the distrustful : when left and right mobilize together
(2025) Daphi, Priska; Meier, Larissa Daria
This article draws scholarly attention to composite protests of the distrustful – a recurring but so far under-researched type of political mobilization. We argue that the combination of three key characteristics is constitutive for this type of protest: the joint mobilization of (far-)right and left-wing groups, high levels of political distrust among its participants and a propensity for conspiracy narratives. We show how such protests reoccur across different issue areas in Southern and Western Europe since at least 2014. We call for more detailed scholarly engagement with this phenomenon not only due to its growing presence but also due to its potentially wide-ranging societal and political consequences, including the normalization of far-right discourses and ideas. As such, we need a better understanding of the conditions that facilitate composite protests of the distrustful and the impacts they may have. This, we contend, is fundamental to understanding current transformations of European political conflicts and protests and to shed light on key contemporary developments, such as challenges to liberal democracy.