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JLUpub ist das institutionelle Repositorium der Justus-Liebig-Universität.
JLUpub bietet Mitgliedern und Angehörigen der Universität die Möglichkeit neben wissenschaftlichen Dokumenten auch Forschungsdaten elektronisch zu veröffentlichen und dauerhaft zugänglich zu machen. Alle Veröffentlichungen erhalten einen Digital Object Identifier (DOI) und werden über nationale und internationale Bibliothekskataloge sowie Suchmaschinen nachgewiesen und auffindbar.
Neue Veröffentlichungen:
Item type: Item , Chronic effects of exposure to polyethylene microplastics may be mitigated at the expense of growth and photosynthesis in reef-building corals(2024) Rades, Marvin; Poschet, Gernot; Gegner, Hagen; Wilke, Thomas; Reichert, JessicaItem type: Item , Synthesis and investigation of a meta[6]cycloparaphenylene gold(i) N-heterocyclic carbene complex(2024) Bernt, Felix; Leonhardt, Christopher M.; Schatz, Dominic; Wegner, Hermann A.Meta[n]cycloparaphenylenes (m[n]CPPs) as well as N-heterocyclic carbene (NHC) gold(I)-complexes are intriguing building blocks for material and life sciences due to their extraordinary structures resulting in unique photophysical properties. Herein, we report the combination of a m[6]CPP with a N-heterocyclic carbene serving as a ligand in a linear gold(I)-complex possessing the form [AuBr(NHC)]. Solid-state structures of both the precursor and the complex are presented and discussed. Moreover, we investigated the luminescence properties of both the imidazolium intermediate and the corresponding gold(I)-complex.Item type: Item , Harnessing RNA interference for the control of Fusarium species: A critical review(2024) Liu, Caihong; Kogel, Karl-Heinz; Ladera-Carmona, MariaFusarium fungi are a pervasive threat to global agricultural productivity. They cause a spectrum of plant diseases that result in significant yield losses and threaten food safety by producing mycotoxins that are harmful to human and animal health. In recent years, the exploitation of the RNA interference (RNAi) mechanism has emerged as a promising avenue for the control of Fusarium-induced diseases, providing both a mechanistic understanding of Fusarium gene function and a potential strategy for environmentally sustainable disease management. However, despite significant progress in elucidating the presence and function of the RNAi pathway in different Fusarium species, a comprehensive understanding of its individual protein components and underlying silencing mechanisms remains elusive. Accordingly, while a considerable number of RNAi-based approaches to Fusarium control have been developed and many reports of RNAi applications in Fusarium control under laboratory conditions have been published, the applicability of this knowledge in agronomic settings remains an open question, and few convincing data on RNAi-based disease control under field conditions have been published. This review aims to consolidate the current knowledge on the role of RNAi in Fusarium disease control by evaluating current research and highlighting important avenues for future investigation.Item type: Item , How to increase nature connectedness? Effectiveness and mechanisms of a gratitude journal intervention(2024) Samus, Andreas; Dickinson, Katharine J. M.; Freeman, Claire; van Heezik, YolandaNature connectedness can promote pro-environmental behaviour and psychological well-being, but little is known about how nature connectedness can be strengthened. Interventions that seek to enhance nature connectedness by promoting direct nature contact may be impractical because urban areas often lack opportunities for interactions with nature in the daily lives of people. This study examines the effects of a gratitude journal exercise on nature connectedness, psychological well-being, and engagement in wildlife gardening. Participants (N = 114) were either asked to write down daily three things relating to nature that they were grateful for over a 14-day period or they were assigned to one of two control groups (a traditional gratitude condition and an activity list condition). Compared to the two control groups, there were no significant differences in any of the outcome variables during the 14-day period and at 1-week and 3-month follow-ups. However, significant increases in all those outcome variables emerged independent of the group. Qualitative data analysis suggests that the journal exercise promoted increases in the outcome variables by generating self-knowledge as well as positive emotions and attitudes. Moreover, participants noted that the journal activity made them think about nature in new ways, presumably through answering daily survey questions on nature connectedness. We suggest that the mere activity of regularly reflecting on one's relationship with nature may increase nature connectedness. Interventions that encourage people to contemplate the interconnectedness between themselves and nature could be a viable strategy to strengthen human–nature relationships, especially in urban areas that lack opportunities for interactions with nature. The findings of this study can inform future research concerned with the processes of strengthening nature connectedness and the design of interventions that employ nature-based journal exercises.Item type: Item , Identification of differentially expressed genes in human testis biopsies with defective spermatogenesis(2024) Kothalawala, Shashika D.; Günther, Stefan; Schuppe, Hans-Christian; Pilatz, Adrian; Wagenlehner, Florian; Kliesch, Sabine; O'Donnell, Liza; Fietz, DanielaPurpose: Sperm morphology and motility are major contributors to male-factor infertility, with many genes predicted to be involved. This study aimed to elucidate differentially expressed transcripts in human testis tissues of normal and abnormal spermatogenesis that could reveal new genes that may regulate sperm morphology and function. Methods: Human testis biopsies were collected from men with well-characterized phenotypes of normal spermatogenesis, spermatid arrest, and Sertoli cell-only phenotype, and transcriptional differences were quantified by RNA-sequencing (RNA-Seq). Differentially expressed genes (DEGs) were filtered based on predominant expression in spermatids and gene functional annotations relevant to sperm morphology and motility. Selected 10 DEGs were validated by qRT-PCR and the localization of two proteins was determined in testis biopsies. Results: The analysis revealed 6 genes (SPATA31E1, TEKT3, SLC9C1, PDE4A, CFAP47, and TNC) that are excellent candidates for novel genes enriched in developing human sperm. The immunohistochemical localization of two proteins, ORAI1 and SPATA31E1, in testis biopsies, verified that both are expressed in developing human germ cells, with SPATA31E1 enriched in late spermatocytes and spermatids. Conclusion: This study identified human germ cell-enriched genes that could play functional roles in spermiogenesis and could thus be important in the development of morphologically normal, motile sperm.