Publikationen im Open Access gefördert durch die UB
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Auflistung Publikationen im Open Access gefördert durch die UB nach Auflistung nach Fachbereich/Einrichtung "FB 08 - Biologie und Chemie"
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Item 1+1≥2? Norbornadiene-Azobenzene Molecules as Multistate Photoswitches(2021) Kunz, Anne; Wegner, Hermann A.Item 1,1,2-Ethenetriol: The Enol of Glycolic Acid, a High-Energy Prebiotic Molecule(2021) Mardyukov, Artur; Keul, Felix; Schreiner, Peter R.Item 1,1-Ethendiol – Das lange Zeit schwer fassbare Enol der Essigsäure(2020) Mardyukov, Artur; Eckhardt, André K.; Schreiner, Peter R.Item 1,1-Ethenediol: The Long Elusive Enol of Acetic Acid(2020) Mardyukov, Artur; Eckhardt, André K.; Schreiner, Peter R.Item 1,2-Carboboration of Arylallenes by In Situ Generated Alkenylboranes for the Synthesis of 1,4-Dienes(2022) Averdunk, Arthur; Hasenbeck, Max; Müller, Tizian; Becker, Jonathan; Gellrich, UrsItem 2D-Coordination Polymers Constituted from Indium Halides and Dipyridyl N-Donor Ligands(2021) Schäfer, Thomas C.; Becker, Jonathan; Sedykh, Alexander E.; Müller-Buschbaum, KlausItem 3D-surface MALDI mass spectrometry imaging for visualising plant defensive cardiac glycosides in Asclepias curassavica(2021) Dreisbach, Domenic; Petschenka, Georg; Spengler, Bernhard; Bhandari, Dhaka R.Item A Comparative Review of Electrolytes for Organic-Material-Based Energy-Storage Devices Employing Solid Electrodes and Redox Fluids(2020) Chen, Ruiyong; Bresser, Dominic; Saraf, Mohit; Gerlach, Patrick; Balducci, Andrea; Kunz, Simon; Schröder, Daniel; Passerini, Stefano; Chen, JunItem A Complex Network of Sigma Factors and sRNA StsR Regulates Stress Responses in R. sphaeroides(2021) Eisenhardt, Katrin M. H.; Remes, Bernhardt; Grützner, Julian; Spanka, Daniel-Timon; Jäger, Andreas; Klug, GabrieleItem A dominant clonal lineage of Streptococcus uberis in cattle in Germany(2022) Fenske, Linda; Noll, Irene; Blom, Jochen; Ewers, Christa; Semmler, Torsten; Fawzy, Ahmad; Eisenberg, TobiasItem A Facile and Inexpensive Way to Synthesize N-trifluoromethyl Compounds(2022) Schaub, Stefan; Becker, Jonathan; Schindler, SiegfriedItem A high-resolution map of functional miR-181 response elements in the thymus reveals the role of coding sequence targeting and an alternative seed match(2024) Verheyden, Nikita A; Klostermann, Melina; Brüggemann, Mirko; Steede, Hanna M; Scholz, Anica; Amr, Shady; Lichtenthaeler, Chiara; Münch, Christian; Schmid, Tobias; Zarnack, Kathi; Krueger, AndreasMicroRNAs (miRNAs) are critical post-transcriptional regulators in many biological processes. They act by guiding RNA-induced silencing complexes to miRNA response elements (MREs) in target mRNAs, inducing translational inhibition and/or mRNA degradation. Functional MREs are expected to predominantly occur in the 3′ untranslated region and involve perfect base-pairing of the miRNA seed. Here, we generate a high-resolution map of miR-181a/b-1 (miR-181) MREs to define the targeting rules of miR-181 in developing murine T cells. By combining a multi-omics approach with computational high-resolution analyses, we uncover novel miR-181 targets and demonstrate that miR-181 acts predominantly through RNA destabilization. Importantly, we discover an alternative seed match and identify a distinct set of targets with repeat elements in the coding sequence which are targeted by miR-181 and mediate translational inhibition. In conclusion, deep profiling of MREs in primary cells is critical to expand physiologically relevant targetomes and establish context-dependent miRNA targeting rules.Item A Long-Lived Azafullerenyl Radical Stabilized by Supramolecular Shielding with a [10]Cycloparaphenylene(2019) Stergiou, Anastasios; Rio, Jérémy; Griwatz, Jan H.; Arcon, Denis; Wegner, Hermann A.; Ewels, Christopher P.; Tagmatarchis, NikosItem A major checkpoint for protein expression in Rhodobacter sphaeroides during heat stress response occurs at the level of translation(2021) McIntosh, Matthew; Köchling, Thorsten; Latz, Anna; Kretz, Jonas; Heinen, Sandra; Konzer, Anne; Klug, GabrieleItem A mechanistic investigation of the Li10GeP2S12|LiNi1-x-yCoxMnyO2 interface stability in all-solid-state lithium batteries(2021) Zuo, Tong-Tong; Rueß, Raffael; Pan, Ruijun; Walther, Felix; Rohnke, Marcus; Hori, Satoshi; Kanno, Ryoji; Schröder, Daniel; Janek, JürgenItem A Mechanistic Study on the Reaction of Non-Heme Diiron(III)-Peroxido Complexes with Benzoyl Chloride(2021) Lerch, Markus; Achazi, Andreas J.; Mollenhauer, Doreen; Becker, Jonathan; Schindler, SiegfriedItem A Modular Synthesis of Substituted Cycloparaphenylenes(2022) Kohrs, Daniel; Becker, Jonathan; Wegner, Hermann A.Item A new lipoxygenase from the agaric fungus Agrocybe aegerita: Biochemical characterization and kinetic properties(2019) Karrer, Dominik; Rühl, MartinOxylipins are metabolites with a variety of biological functions. However, the biosynthetic pathway is widely unknown. It is considered that the first step is the oxygenation of polyunsaturated fatty acids like linoleic acid. Therefore, a lipoxygenase (LOX) from the edible basidiomycete Agrocybe aegerita was investigated. The AaeLOX4 was heterologously expressed in E. coli and purified via affinity chromatography and gel filtration. Biochemical properties and kinetic parameters of the purified AaeLOX4 were determined with linoleic acid and linolenic acid as substrates. The obtained Km, vmax and kcat values for linoleic acid were 295.5 μM, 16.5 μM · min⁻¹ · mg⁻¹ and 103.9 s⁻¹ , respectively. For linolenic acid Km, vmax and kcat values of 634.2 μM, 19.5 μM · min⁻¹ · mg⁻¹ and 18.3 s⁻¹ were calculated. Maximum activities were observed at pH 7.5 and 25 ˚C. The main product of linoleic acid conversion was identified with normal-phase HPLC. This analysis revealed an explicit production of 13-hydroperoxy-9,11-octadecadienoic acid (13-HPOD). The experimental regio specificity is underpinned by the amino acid residues W384, F450, R594 and V635 considered relevant for regio specificity in LOX. In conclusion, HPLC-analysis and alignments revealed that Aae-LOX4 is a 13-LOX.Item A new species of Petrolisthes (Crustacea, Anomura, Porcellanidae) inhabiting vermetid formations (Mollusca, Gastropoda, Vermetidae) in the southern Caribbean Sea(2019) Hiller, Alexandra; Werding, BerndItem A protocol for laser microdissection (LMD) followed by transcriptome analysis of plant reproductive tissue in phylogenetically distant angiosperms(2019) Kivivirta, Kimmo; Herbert, Denise; Lange, Matthias; Beuerlein, Knut; Altmüller, Janine; Becker, Annette