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dc.contributor.authorRoller, Fritz C.
dc.contributor.authorSchüßler, Armin
dc.contributor.authorKremer, Nils
dc.contributor.authorHarth, Sebastian
dc.contributor.authorKriechbaum, Steffen D.
dc.contributor.authorWiedenroth, Christoph B.
dc.contributor.authorGuth, Stefan
dc.contributor.authorBreithecker, Andreas
dc.contributor.authorRichter, Manuel
dc.contributor.authorTello, Khodr
dc.contributor.authorSeeger, Werner
dc.contributor.authorMayer, Eckhard
dc.contributor.authorKrombach, Gabriele A.
dc.date.accessioned2023-04-13T12:06:26Z
dc.date.available2023-04-13T12:06:26Z
dc.date.issued2023
dc.identifier.urihttps://jlupub.ub.uni-giessen.de//handle/jlupub/16195
dc.identifier.urihttp://dx.doi.org/10.22029/jlupub-15577
dc.description.abstractBackground: Parametric imaging has taken a steep rise in recent years and non-cardiac applications are of increasing interest. Therefore, the aim of our study was to assess right (RV) and left ventricular (LV) blood pool T1 and T2 values in patients with chronic thromboembolic pulmonary hypertension (CTEPH) compared to control subjects and their correlation to pulmonary hemodynamic. Methods: 26 patients with CTEPH (mean age 64.8 years ± 12.8 SD; 15 female), who underwent CMR and right heart catheterization (RHC) before and 6-months after balloon pulmonary angioplasty (BPA), were retrospectively included. Ventricular blood pool values were measured, compared to control subjects (mean age 40.5 years ± 12.8 SD; 16 female) and correlated to invasive measures (CI, mPAP, PVR). Results: In both, control subjects and CTEPH patients, RVT1 and RVT2 were significantly reduced compared to LVT1 and LVT2. Compared to control subjects, RVT2 was significantly reduced in CTEPH patients (p = 0.0065) and increased significantly after BPA (p = 0.0048). Moreover, RVT2 was positively correlated with CI and negatively correlated with mPAP and PVR before (r = 0.5155, r = −0.2541, r = −0.4571) and after BPA (r = 0.4769, r = −0.2585, r = −0.4396). Conclusion: Ventricular blood pool T2 mapping might be novel non-invasive CMR imaging marker for assessment of disease severity, prognosis, follow-up and even therapy monitoring in PH.
dc.language.isoen
dc.rightsNamensnennung 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCMR
dc.subjectCTEPH
dc.subjectparametric imaging
dc.subjectT1 mapping
dc.subjectT2 mapping
dc.subject.ddcddc:610
dc.titleValue of Right and Left Ventricular T1 and T2 Blood Pool Mapping in Patients with Chronic Thromboembolic Hypertension before and after Balloon Pulmonary Angioplasty
dc.typearticle
local.affiliationFB 11 - Medizin
local.source.spage1
local.source.epage10
local.source.journaltitleJournal of Clinical Medicine
local.source.volume12
local.source.articlenumber2092
local.source.urihttps://doi.org/10.3390/jcm12062092


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