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Human dander as a potential allergen source in atopic dogs : allergen characterization and IgE-profiling

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Perennial indoor allergens, among them house dust mites and molds areknown to be important inducers of IgE-mediated hypersensitivity reactions in dogs. Human dander (HD), an important constituent of house dust may also be a major cause of atopic disease in dogs. So far, HD has been poorly characterized as an allergenic source and the role HD plays in veterinary medicine is unclear. The aims of this study were to characterize two available HD extracts, thuscompleting a representative panel of allergens used to screen four typical dog populations for their allergen-specific IgE profiles. A further aim of this study was the identification of specific IgE-binding proteins in HD extract and the elucidation of their biological nature.

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Giessen : VVB Laufersweiler 2006

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