Mini-Review: Immunogenic epitopes in apolipoprotein B-100 for atheroprotective immunization
Datum
2024
Autor:innen
Betreuer/Gutachter
Weitere Beteiligte
Herausgeber
Zeitschriftentitel
ISSN der Zeitschrift
Bandtitel
Verlag
Zitierlink
Zusammenfassung
Here, we provide a concise overview of recent developments in the identification of immunogenic epitopes in human apolipoprotein B-100 for immunization against atherosclerotic cardiovascular disease. Major steps forward toward a clinical application of vaccines include the design of humanized mouse models, tetramer-based identification of antigen-specific T cells, and novel analysis tools, such as single-cell RNA sequencing and cytometry by time of flight, to assess temporal and spatial changes in immune cells in atherosclerotic cardiovascular disease.
Beschreibung
Inhaltsverzeichnis
Anmerkungen
Erstpublikation in
Frontiers in Cardiovascular Medicine 11 (2024), 1 - 6, 1448664